LL37 5MG

LL37 is a synthetic peptide derived from the human cathelicidin antimicrobial protein, commonly studied in the context of antimicrobial research, immune modulation, and wound healing. This product provides a research-grade formulation of LL37 at a concentration of 5 milligrams.

Research Context

The human cathelicidin LL37 (also known as CAP-18) is a broad-spectrum antimicrobial peptide with activity against a wide range of bacteria, fungi, and even enveloped viruses. Its natural role in the human immune system includes host defense, inflammation regulation, and tissue remodeling. Due to its potential applications in antimicrobial studies, wound healing research, and molecular biology, LL37 is a widely investigated compound.

Research Overview

LL37 has been extensively studied for its antimicrobial properties, including resistance against antibiotic-resistant strains such as methicillin-resistant Staphylococcus aureus (MRSA). In vitro and in vivo experiments have demonstrated its efficacy in combating microbial biofilms and inhibiting bacterial growth. Additionally, LL37 plays a role in the innate immune response, influencing cytokine production and modulating inflammatory pathways. Its application in preclinical studies often explores mechanisms of immune regulation, tissue repair, and antimicrobial defense.

Key Research Focus Areas

• Antimicrobial Activity: Evaluation of LL37’s efficacy against various pathogens, including Gram-positive and Gram-negative bacteria, fungi, and viruses.
• Innate Immunity: Investigation of LL37’s role in immune cell signaling, cytokine modulation, and inflammation response.
• Wound Healing: Research into LL37’s potential in accelerating tissue repair and reducing infection risk in wound models.
• Antimicrobial Resistance: Studies on LL37’s ability to counteract bacterial resistance mechanisms, including biofilm formation.
• Molecular Biology Applications: Use in experiments involving protein interactions, gene expression, and structural biology.

Product Formulation

This LL37 peptide is supplied as a lyophilized powder for reconstitution in an appropriate buffer or solvent suitable for research applications. The 5-mg dose is intended for use in controlled laboratory settings under the supervision of qualified personnel. Precise handling and storage conditions must adhere to research protocols.

For research use only. Not for human or animal consumption.